Growth factor-induced release of placental alkaline phosphatase from human syncytiotrophoblast membranes
نویسندگان
چکیده
منابع مشابه
Angiotensin II receptor in human placental syncytiotrophoblast plasma membranes.
Previous studies have reported the presence of high-affinity angiotensin II (Ang II) binding sites in human placental tissue, but it has not been determined whether these are located in brush border (BBM) or basolateral plasma (BPM) membranes of the syncytiotrophoblast. Our findings provide no evidence for Ang II receptors in BBM, yet they reveal a single class of binding sites in BPM preparati...
متن کاملNucleotide and amino acid sequences of human intestinal alkaline phosphatase: close homology to placental alkaline phosphatase.
A cDNA clone for human adult intestinal alkaline phosphatase (ALP) [orthophosphoric-monoester phosphohydrolase (alkaline optimum); EC 3.1.3.1] was isolated from a lambda gt11 expression library. The cDNA insert of this clone is 2513 base pairs in length and contains an open reading frame that encodes a 528-amino acid polypeptide. This deduced polypeptide contains the first 40 amino acids of hum...
متن کاملUse of monoclonal antibodies to detect human placental alkaline phosphatase.
Convenient, sensitive, and specific solid-phase immunoassays involving monoclonal antibody are described for the determination of human placental alkaline phosphatase (hPLAP). An endogenous enzyme immunoassay combined the specificity of the immunological and the enzymatic reactions. Alternatively, a solid-phase "sandwich" radioimmunoassay involving immobilized polyclonal rabbit anti-hPLAP in co...
متن کاملHuman placental alkaline phosphatase in benign and malignant ovarian neoplasia.
In benign and malignant ovarian tumor patients, human placental alkaline phosphatase (HPLAP) was determined in serum and extracts from surgical tumor biopsies using a highly specific enzyme-antigen immunoassay based on a mouse monoclonal antibody (E6) to HPLAP. Serum HPLAP levels greater than or equal to 0.1 unit/liter were found in 58% of ovarian cancer patients. Serum carcinoembryonic antigen...
متن کاملHuman placental alkaline phosphatase and acute lung injury.
catheter pleurodesis in the treatment of malignant effusions. Chest 1986; 89:482S 6 Mitchell ME, Avery JA, Alberts WM, Goldman AL. Drainage of pleural effusions with a percutaneous pneumothorax catheter. Chest 1986; 89:482S 7 Sahn SA, Good JT. The effect ofcommon sclerosing agents on the rabbit pleural space. Am Rev Respir Dis 1981; 124:65-67 8 Cannon WB, Wolfe WG. Chest tube placement for pneu...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Reproduction
سال: 1994
ISSN: 1470-1626,1741-7899
DOI: 10.1530/jrf.0.1000071